نوع مقاله : مقاله پژوهشی

نویسندگان

1 پژوهشکده‌ کاربرد پرتوها، پژوهشگاه علوم و فنون هسته‌ای، سازمان انرژی اتمی، صندوق پستی: 14155-1339، تهران- ایران

2 دپارتمان سرطان‌شناسی، بیمارستان دانشگاه آرهوس، آرهوس- دانمارک

3 پژوهشکده‌ی فوتونیک و فناوری‌های کوانتومی، پژوهشگاه علوم و فنون هسته‌ای، سازمان انرژی اتمی ایران، صندوق پستی: 14155-1339، تهران ـ ایران

4 دپارتمان پزشکی، دانشگاه آرهوس، آرهوس- دانمارک

چکیده

یکی از جدیدترین و مؤثرترین روش‌­ها به ­منظور ردیابی بلادرنگ بافت هدف در پرتودرمانی خارجی سرطان سینه چپ، به کارگیری سیستم ویژن- آرتی است. در این سیستم در طول فرایند درمان حرکات سطح بدن به ­صورت سه ­بعدی با کمک دوربین‌های نوری و استفاده از روش‌­های پردازش و برازش تصویر تخمین زده می‌­شود. هدف از این پژوهش، بررسی کمّی و کیفی دقت پرتودرمانی سرطان سینه چپ با هدایت سیستم ویژن- آرتی و به روش حبس تنفس عمیق است. بدین منظور 5 بیمار مبتلا به سرطان سینه چپ با پرتودرمانی به روش تنفس عمیق با هدایت سیستم ویژن- آرتی در بیمارستان آرهوس کشور دانمارک تحت درمان قرار گرفتند. نتایج نشان داد در 5 جلسه از 15 جلسه درمانی، در یک بیمار از 5 بیمار، قلب به طور ناخواسته به میزان 6/0 تا cm 9/0 وارد ناحیه تابش شده بود. با به کارگیری معیار ون- هرک، حاشیه PTV مورد نیاز در اطراف تومور جهت پوشش خطای موقعیت­‌دهی به بیمار mm 38/2 و خطای حین درمان برای دو باریکه درمانی اصلی شماره 1 و 2 به ­ترتیب برابر با mm 3 و mm 12/4 به دست آمد.

کلیدواژه‌ها

عنوان مقاله [English]

Investigation of the accuracy of deep inspiration breath hold left-sided breast cancer radiotherapy using a surface guiding system

نویسندگان [English]

  • S. Nankali 1 2
  • A. Zirak 3
  • A. Movafeghi 1
  • P.R. Poulsen 2 4

1 Radiation Application Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 1339-14155, Tehran - Iran

2 Radiation Application Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 1339-14155, Tehran - Iran

3 Photonics and Quantum Technology Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 1339-14155, Tehran - Iran

4 Department of Oncology, Aarhus University Hospital, Aarhus – Danmark

چکیده [English]

Vision-RT system is one of the most effective methods for real-time estimation of target location in external beam radiotherapy. Vision-RT tracks the patient’s surface before and during radiation therapy to improve treatment accuracy. Using proprietary 3D stereo camera units, Vision-RT system tracks the skin surface, compares it to the ideal position, and can automatically signal to the treatment delivery system. The purpose of this study is to investigate the accuracy of Vision RT guided deep inspiration breath-hold left-sided breast cancer radiotherapy. Five patients with left-sided breast cancer were treated by Vision RT guided deep inspiration breath-hold at Aarhus university hospital. Based on the results, in one out of five patients, the undesired heart extended to 0.6-0.9 cm into the treatment fields in 5 out of 15 treatment fractions. Moreover, the required PTV margin to account for patient setup error and intra-fractional error of the first and second treatment field was 2.38 mm, 3 mm and 4.12 mm, respectively.

کلیدواژه‌ها [English]

  • Surface guided radiotherapy
  • Deep inspiration breath hold
  • left-sided breast cancer
  • Image guided radiotherapy
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