In cooperation with the Iranian Nuclear Society

Document Type : Scientific Note

Authors

Radiation Applications Research School, Nuclear Science and Technology Research Institute, P.O.Box: 1339-14155, Tehran-Iran

Abstract

Considering the importance of quality control of radiotherapy systems and 3D dose mapping possibility done with a Fricke agarose gel dosimeter, this dosimeter based on ferrous solution and agarose gel was prepared. The prepared Fricke gel dosimeters was investigated under gamma irradiation with a dose range up to 20 Gy. Concerning the effect of the gel dosimeter constituent’s concentration on the response of the dosimeter, different compositions were surveyed for better sensitivity and repeatability. So, the responses were evaluated for different concentrations of ferrous ion, sulphuric acid, and the indicator. We found that the Fricke agarose gel dosimeter has a linear behavior up to 20 Gy. In addition, the best composition of Fricke agarose gel dosimeter with high sensitivity and stability was determined to be 0.2 mM ferrous, 25 mM sulphuric acid, and 0.15 mM Xylenol orange.

Highlights

1. L.E. Olsson, et al., MR imaging of absorbed dose distributions for radiotherapy using ferrous sulphate gels, Physics in Medicine & Biology, 35(12), 1623 (1990).

 

2. L.E. Olsson, et al, Ferrous sulphate gels for determination of absorbed dose distributions using MRI technique:  basic studies, Physics in Medicine & Biology, 34, 43 (1989).

 

3. M.A. Bero, Dosimetric properties of a radiochromic gel detector fordiagnostic X-rays, Nuclear Instruments and Methods in Physics Research, A., 580, 186 (2007).

 

4. S.A. Back, et al, Improvements in absorbed dose measurements for external radiation therapy using ferrous dosimeter gel and MR imaging (FeMRI), Physics in Medicine & Biology, 43, 261 (1998).

 

5. C.C. Cavinato, L.L. Campos, Study of Fricke gel dosimeter response for different gel quality, Journal of Physics: Conference Series, 249, 012064 (2010).

 

6. A.M. Galante, et al., MRI study of radiation effect on Fricke gel solutions, Radiation Measurements, 43 (2), 550 (2008).

 

7. M.A. Bero, et al., Tissue-equivalent gel for non-invasive spatial radiation dose Measurements, Nuclear Instruments and Methods in Physics Research, B., 166, 820 (2000).

 

8. L.E. Olsson, et al., A New Dosimeter Based on Ferrous Sulphate Solution and Agarose Gel, Applied Radiation Isotopes, 42(11), 1081 (1991).

 

9. Appelby A. A. Leghrouz, Imaging of radiation dose by visible color development in ferrousagarosexylenol orange gels, Medical Physics, 18, 309 (1991).

 

10. M. Marrale, et al., Correlation between ferrous ammonium sulfate concentration, sensitivity and stability of Fricke gel dosimeters exposed to clinical X-ray beams, Nuclear Instruments and Methods in Physics Research, B., 335, 54 (2014).

 

11. M. Dehghan, et al., Evaluation of Ferrous-Agarose-Xylenol Gel Properties in Radiation Dosimetry, J. Biomedical Physics Engineering, 2(2), (2012).

 

12. G. Gambarini, et al., Study of optical absorbance and MR relaxation of Fricke xylenol orange gel dosimeters, Radiation Measurements, 103, 25 (2017).

 

13. L.J. Schreiner, Review of Fricke gel dosimetry, Journal of Physics, Conference Series, 3, 9 (2004).

Keywords

1. L.E. Olsson, et al., MR imaging of absorbed dose distributions for radiotherapy using ferrous sulphate gels, Physics in Medicine & Biology, 35(12), 1623 (1990).
 
2. L.E. Olsson, et al, Ferrous sulphate gels for determination of absorbed dose distributions using MRI technique:  basic studies, Physics in Medicine & Biology, 34, 43 (1989).
 
3. M.A. Bero, Dosimetric properties of a radiochromic gel detector fordiagnostic X-rays, Nuclear Instruments and Methods in Physics Research, A., 580, 186 (2007).
 
4. S.A. Back, et al, Improvements in absorbed dose measurements for external radiation therapy using ferrous dosimeter gel and MR imaging (FeMRI), Physics in Medicine & Biology, 43, 261 (1998).
 
5. C.C. Cavinato, L.L. Campos, Study of Fricke gel dosimeter response for different gel quality, Journal of Physics: Conference Series, 249, 012064 (2010).
 
6. A.M. Galante, et al., MRI study of radiation effect on Fricke gel solutions, Radiation Measurements, 43 (2), 550 (2008).
 
7. M.A. Bero, et al., Tissue-equivalent gel for non-invasive spatial radiation dose Measurements, Nuclear Instruments and Methods in Physics Research, B., 166, 820 (2000).
 
8. L.E. Olsson, et al., A New Dosimeter Based on Ferrous Sulphate Solution and Agarose Gel, Applied Radiation Isotopes, 42(11), 1081 (1991).
 
9. Appelby A. A. Leghrouz, Imaging of radiation dose by visible color development in ferrousagarosexylenol orange gels, Medical Physics, 18, 309 (1991).
 
10. M. Marrale, et al., Correlation between ferrous ammonium sulfate concentration, sensitivity and stability of Fricke gel dosimeters exposed to clinical X-ray beams, Nuclear Instruments and Methods in Physics Research, B., 335, 54 (2014).
 
11. M. Dehghan, et al., Evaluation of Ferrous-Agarose-Xylenol Gel Properties in Radiation Dosimetry, J. Biomedical Physics Engineering, 2(2), (2012).
 
12. G. Gambarini, et al., Study of optical absorbance and MR relaxation of Fricke xylenol orange gel dosimeters, Radiation Measurements, 103, 25 (2017).
 
13. L.J. Schreiner, Review of Fricke gel dosimetry, Journal of Physics, Conference Series, 3, 9 (2004).