Gamma ray measurement in various research fields requires high efficient detectors. In photon dosimetry, NaI(Tl) scintillation detector as one of the inorganic scintillation detector is noticeable, due to have the high amount of light output. In this study, the basics determination of photon dosimetry for the NaI(Tl) scintillation detector utilizing the Monte Carlo code (MCNPX) and using different methods of dose calculation (tally F6, * F4, + F6 and * F8) is studied. Regularly, the output of a radiation detector (counting the number of pulses) cannot be used to determine the radiation dose value. Therefore, in this study the spectro-dosimetry method based on software method is used to find out the value of the conversion coefficients to convert the detector spectrum to the value of air karma. In this method, the radiation dosimetry response is obtained with use of the MCNPX code simulation. The response function of the NaI(Tl) 3"×3" scintillation detector for several specific gamma rays was determined and then the functions of energy dependent conversion coefficients for calculating the dose values were obtained. Finally, with comparison of the measured data and simulation calculations results it is shown that the proposed method has a high accuracy in photon dosimetry
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