Journal of Nuclear Science, Engineering and Technology (JONSAT)
In cooperation with the Iranian Nuclear Society

Separation of Eu Radioisotopes Impurity from Irradiated Natural Sm Target for Purification of 153Sm

Document Type : Research Paper

Authors

S.Z Islami Rad
M Shamsaei
R Gholipour Peyvandi
M Ghannadi Maragheh
A Bahrami Samani
S. Shirvani Arani
Abstract
The 153Sm production by neutron bombardment of a natural samarium target produces 154,155,156Eu impurities. Therefore, it is important to investigate amount of impurities and their separation methods. In this study, 153Sm was separated from Eu radioisotopes by ion exchange chromatography. Natural Sm2O3 powder was dissolved in HNO3 and encapsulated in aluminum foils. The target was irradiated by the Tehran 5MW Research Reactor with the neutron flux of 5´1013 n cm-2 s-1. The irradiated target was dissolved in HCl and was injected into a chromatography column that was packed with Dowex-50Wx8, 200-400 mesh resin. As a result, 153Sm was separated with the recovery yield ofmore than 65% with a purity better than 99.8% from Eu impurities

Highlights

 

 

  1. 1.    M.A. Majali, A.R. Mathakar, H.H. Shimpi, Banerjeea, Sharmila, Samuel, Grace: Studies on the preparation and stability of samarium-153 propylene diamine tetramethylene phosphonate (PDTMP) complex as a bone seeker. Appl. Radiat. Isot. 53(6), 987-991 (2000).

 

  1. 2.    W.K.A. Louw, I.C. Dormehl, van Rensburg A.J., Hugo, N., Alberts, A.S., Forsyth, O.E., Beverly, G., Sweetlove, M.A., Marais, J., Loitter, M.G. van Aswegen, A: Evaluation of samarium-153 and holmium-166-EDTMP in the normal baboon model. Nucl. Med. &. Biol. 23(8), 935-940 (1996).

 

  1. 3.    Qiu, L., Kang, X., Wang, T.: A study on photochemical separation of rare earths the separation of europium from an industrial concentrate material of samarium, europium, and gadolinium. Separ. Sci. Tech. 26(2), 199-221 (1991).

 

  1. 4.    Schwantes, J.M., Sudowe, R., Nitsche, H., Hoffman, D.C.: Applications of solvent extraction in the high-yield multi-process reduction/separation of Eu from excess Sm. J. radioanal. Nucl. Chem. 276(2) (2008).

 

  1. 5.    T, Hirai., I, Komasawa.: Separation of Eu from Sm/Eu/Gd mixture by photoreductive stripping in solvent extraction process. Ind. Eng. Chem. Res. 34 (1), 237–243 (1995).

 

  1. 6.    Balasubramanian, P. S.: Production of radiochemically and radionuclidically pure 153Sm for medical applications. J. Radioanal. Nucl. Chem. 200(1), 43-51 (1995).

 

  1. 7.    Ramamoorthy, N., Saraswathy, P., Das, M.K., Mehra, K.S., Ananthakrishnan, M.: Production logistics and radionuclidic purity aspects of 153Sm for radionuclide therapy. Nuc. Med. commun. 23(1) ,83-89 (2002).

 

  1. 8.    Prabhakar, G., Joshi, Sangeeta.H., Ranganatha, D.K., Umamaheswari, S., Ananthakrishhan, M., Ramamoorthy, N.: Preparation and evaluation of samarium phosphate [153Sm] colloid (SMPC) for possible therapeutic use. Nucl. Med. Biol. 27(4), 353-356 (2000).

 

Keywords

Radionuclide
Samarium-153
Radionuclide Purity
Separation
Dowex-50Wx8 Resin
Ion Exchange Chromatography

  1.  

     

    1. 1.    M.A. Majali, A.R. Mathakar, H.H. Shimpi, Banerjeea, Sharmila, Samuel, Grace: Studies on the preparation and stability of samarium-153 propylene diamine tetramethylene phosphonate (PDTMP) complex as a bone seeker. Appl. Radiat. Isot. 53(6), 987-991 (2000).

     

    1. 2.    W.K.A. Louw, I.C. Dormehl, van Rensburg A.J., Hugo, N., Alberts, A.S., Forsyth, O.E., Beverly, G., Sweetlove, M.A., Marais, J., Loitter, M.G. van Aswegen, A: Evaluation of samarium-153 and holmium-166-EDTMP in the normal baboon model. Nucl. Med. &. Biol. 23(8), 935-940 (1996).

     

    1. 3.    Qiu, L., Kang, X., Wang, T.: A study on photochemical separation of rare earths the separation of europium from an industrial concentrate material of samarium, europium, and gadolinium. Separ. Sci. Tech. 26(2), 199-221 (1991).

     

    1. 4.    Schwantes, J.M., Sudowe, R., Nitsche, H., Hoffman, D.C.: Applications of solvent extraction in the high-yield multi-process reduction/separation of Eu from excess Sm. J. radioanal. Nucl. Chem. 276(2) (2008).

     

    1. 5.    T, Hirai., I, Komasawa.: Separation of Eu from Sm/Eu/Gd mixture by photoreductive stripping in solvent extraction process. Ind. Eng. Chem. Res. 34 (1), 237–243 (1995).

     

    1. 6.    Balasubramanian, P. S.: Production of radiochemically and radionuclidically pure 153Sm for medical applications. J. Radioanal. Nucl. Chem. 200(1), 43-51 (1995).

     

    1. 7.    Ramamoorthy, N., Saraswathy, P., Das, M.K., Mehra, K.S., Ananthakrishnan, M.: Production logistics and radionuclidic purity aspects of 153Sm for radionuclide therapy. Nuc. Med. commun. 23(1) ,83-89 (2002).

     

    1. 8.    Prabhakar, G., Joshi, Sangeeta.H., Ranganatha, D.K., Umamaheswari, S., Ananthakrishhan, M., Ramamoorthy, N.: Preparation and evaluation of samarium phosphate [153Sm] colloid (SMPC) for possible therapeutic use. Nucl. Med. Biol. 27(4), 353-356 (2000).

     

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