نوع مقاله : مقاله پژوهشی

نویسندگان

1 پژوهشکده رآکتور و ایمنی هسته‌ای، پژوهشگاه علوم و فنون هسته‌ای، سازمان انرژی اتمی ایران، صندوق پستی: 836-14395، تهران - ایران

2 گروه بیوفیزیک، دانشکده علوم زیستی، دانشگاه تربیت مدرس، صندوق پستی: 154-14115، تهران - ایران

3 پژوهشکده کاربرد پرتوها، پژوهشگاه علوم و فنون هسته‌ای، سازمان انرژی اتمی ایران، صندوق پستی: 836-14395، تهران ـ ایران

10.24200/nst.2023.1345

چکیده

تأثیر پرتوگیری مزمن بر ساکنین مناطق با پرتوزایی طبیعی بالا در شهر رامسر، با استفاده از روش سیتوژنتیک سنجش هستک­های متوقف شده در مرحله سیتوکینز و مقایسه­ی نتایج میان دو گروه مورد مطالعه و کنترل، مورد بررسی قرار گرفت. نتایج نشان داد اختلاف معنی­داری (001/0< P) در میانگین فرکانس هستک­های شمارش شده در لنفوسیت­های خون محیطی گروه مورد مطالعه (ساکن در منطقه­ی با پرتوزایی طبیعی بالای شهر رامسر) و گروه کنترل (ساکن در شهر تنکابن) وجود دارد. هم­چنین، بعد از پرتودهی نمونه­ها، گروه کنترل، افزایش بیش­تری را در فرکانس هستک­ها نسبت به گروه مورد مطالعه نشان داد و این امر، شاهدی بر وجود پدیده پاسخ تطبیقی پرتوی، در ساکنین مناطق با پرتوزایی طبیعی بالا در شهر رامسر می­باشد. همبستگی میان فرکانس هستک­ها و سن، در گروه کنترل بیش­تر از گروه مورد مطالعه مشاهده شد.

کلیدواژه‌ها

عنوان مقاله [English]

Chronic exposure effect study on Ramsar high background natural radiation areas (HBNRAs) residents using micronucleus assay

نویسندگان [English]

  • F. Abbasi Siar 1 2
  • P. Abdolmaleki 2
  • A. Haeri 1
  • M. Hosseini Pooya 3

1 Reactor and Nuclear Safety Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 14395-836, Tehran - Iran

2 Reactor and Nuclear Safety Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 14395-836, Tehran - Iran

3 Radiation Application Research School, Nuclear Science and Technology Research Institute, P.O.Box: 14395-836, Tehran - Iran

چکیده [English]

The effect of chronic exposure on Ramsar HBNRAs inhabitants' health was studied using Cytokinesis Blocked Micronucleus (CBMN) Assay. The results showed a significant difference (P <0.001) in the mean frequency of micronucleus of the study group, or resident in Ramsar HBNRAs, and the control group, which were selected from Tonekabon, a city near Ramsar. Significant differences (P <0.001) were observed between the mean micronucleus frequency after irradiation of blood samples, which means that after irradiation of blood samples, the control group showed a higher increase in micronuclei frequency than the study group that can be as a result of the existence of a radio adaptive response in Ramsar HBNRAs. The correlation was observed between the frequency of micronucleus and age in control groups but was not obtained for the study group.

کلیدواژه‌ها [English]

  • High natural radiation
  • Biological dosimetry
  • Micro nucleus (MN) assay
  • Chronic exposure
  • Radioadaptive response
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