نوع مقاله : مقاله پژوهشی
نویسندگان
1 پژوهشکده رآکتور و ایمنی هسته‌ای، پژوهشگاه علوم و فنون هسته‌ای، سازمان انرژی اتمی ایران، صندوق پستی: 836-14395، تهران - ایران
2 گروه بیوفیزیک، دانشکده علوم زیستی، دانشگاه تربیت مدرس، صندوق پستی: 154-14115، تهران - ایران
3 پژوهشکده کاربرد پرتوها، پژوهشگاه علوم و فنون هسته‌ای، سازمان انرژی اتمی ایران، صندوق پستی: 836-14395، تهران ـ ایران
چکیده
تأثیر پرتوگیری مزمن بر ساکنین مناطق با پرتوزایی طبیعی بالا در شهر رامسر، با استفاده از روش سیتوژنتیک سنجش هستکهای متوقف شده در مرحله سیتوکینز و مقایسهی نتایج میان دو گروه مورد مطالعه و کنترل، مورد بررسی قرار گرفت. نتایج نشان داد اختلاف معنیداری (001/0< P) در میانگین فرکانس هستکهای شمارش شده در لنفوسیتهای خون محیطی گروه مورد مطالعه (ساکن در منطقهی با پرتوزایی طبیعی بالای شهر رامسر) و گروه کنترل (ساکن در شهر تنکابن) وجود دارد. همچنین، بعد از پرتودهی نمونهها، گروه کنترل، افزایش بیشتری را در فرکانس هستکها نسبت به گروه مورد مطالعه نشان داد و این امر، شاهدی بر وجود پدیده پاسخ تطبیقی پرتوی، در ساکنین مناطق با پرتوزایی طبیعی بالا در شهر رامسر میباشد. همبستگی میان فرکانس هستکها و سن، در گروه کنترل بیشتر از گروه مورد مطالعه مشاهده شد.
کلیدواژه‌ها
عنوان مقاله [English]
Chronic exposure effect study on Ramsar high background natural radiation areas (HBNRAs) residents using micronucleus assay
نویسندگان [English]
- F. Abbasi Siar 1 2
- P. Abdolmaleki 2
- A. Haeri 1
- M. Hosseini Pooya 3
1 Reactor and Nuclear Safety Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 14395-836, Tehran - Iran
2 Reactor and Nuclear Safety Research School, Nuclear Science and Technology Research Institute, AEOI, P.O.Box: 14395-836, Tehran - Iran
3 Radiation Application Research School, Nuclear Science and Technology Research Institute, P.O.Box: 14395-836, Tehran - Iran
چکیده [English]
The effect of chronic exposure on Ramsar HBNRAs inhabitants' health was studied using Cytokinesis Blocked Micronucleus (CBMN) Assay. The results showed a significant difference (P <0.001) in the mean frequency of micronucleus of the study group, or resident in Ramsar HBNRAs, and the control group, which were selected from Tonekabon, a city near Ramsar. Significant differences (P <0.001) were observed between the mean micronucleus frequency after irradiation of blood samples, which means that after irradiation of blood samples, the control group showed a higher increase in micronuclei frequency than the study group that can be as a result of the existence of a radio adaptive response in Ramsar HBNRAs. The correlation was observed between the frequency of micronucleus and age in control groups but was not obtained for the study group.
کلیدواژه‌ها [English]
- High natural radiation
- Biological dosimetry
- Micro nucleus (MN) assay
- Chronic exposure
- Radioadaptive response
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