مجله علوم، مهندسی و فناوری هسته‌ای

تأثیر زاویه تابش بر عملکرد زیست‌حسگر HIV-1 مبتنی بر بلور فوتونیکی یک‌بعدی

نوع مقاله : مقاله فنی

نویسندگان

مهدی سویزی
مریم علیان‌نژادی

دانشکده فیزیک، دانشگاه سمنان، صندوق پستی: 363-35195، سمنان - ایران

https://doi.org/10.24200/nst.2024.1532.1999
چکیده
شناسایی به موقع ویروس‌ها مثل ویروس نقص ایمنی انسانی (HIV-1) در نقطه مراقبت (POC) می‌تواند منجر به اقدامات پزشکی به موقع، درمان مناسب و کاهش نرخ رشد و گسترس بیماری شود. در این مقاله دو زیست‌حسگر HIV مبتنی بر بلور فوتونیکی یک‌بعدی کامل و حاوی لایه نقص برای تشخیص این ویروس پیشنهاد و مشخصه‌های اصلی این زیست‌حسگرها مثل حساسیت و ضریب کیفیت (ضریب Q) مورد بررسی قرار می‌گیرد. همچنین، تأثیر زاویه تابش بر عملکرد این دو حسگر نیز مورد ارزیابی قرار می‌گیرد. نتایج نشان می‌دهد که حساسیت زیست‌حسگر HIV بر پایه بلور فوتونیکی کامل مستقل از زاویه تابش است در حالی که ضریب Q این حسگر با افزایش زاویه تابش افزایش یافته و مقدار این کمیت تحت زاویه تابش 85 درجه تقریباً 14 برابر بزرگتر از تابش عمودی است. این در حالی است که حساسیت و ضریب Q زیست‌حسگر حاوی لایه نقص تابعی از زاویه تابش است و بیشینه مقدار این کمیت‌ها که در زوایای تابش 65 و 47 درجه اتفاق می‌افتد و به ترتیب برابر با 1056nm/RIU و 12683 می‌باشند. بنابراین، این زیست‌حسگر به عنوان گزینه مناسبی برای تشخیص ویروس HIV پیشنهاد می‌شود.

کلیدواژه‌ها

زیست‌حسگر
حسگر نوری
بلورهای فوتونیکی یک‌بعدی
ویروس نقص ایمنی انسانی

عنوان مقاله English

Effect of irradiation angle on the performance of HIV-1 biosensor based on one-dimensional photonic crystal

نویسندگان English

M. Sovizi
M. Aliannezhadi
Faculty of Physics, Semnan University, P.O.Box: 35195-363, Semnan – Iran
چکیده English

The timely detection of human immunodeficiency virus (HIV) at the point of care (POC) enables prompt medical intervention, and appropriate treatment, and helps reduce the growth rate and spread of the disease. In this paper, two HIV-1 biosensors are proposed: one based on a perfect 1-D photonic crystal (PC) and the other based on a 1-D PC containing a defect layer. The main characteristics of these biosensors, including sensitivity and Q factor, are analyzed. Additionally, the effect of the irradiation angle on the performance of these two sensors is evaluated. The results show that the sensitivity of the HIV-1 biosensor based on the perfect photonic crystal is independent of the irradiation angle. Meanwhile, the Q factor of this sensor increases with an increase in the irradiation angle, with the Q factor at an angle of 85 degrees being nearly 14 times greater than that at normal incidence. On the other hand, both the sensitivity and Q factor of the biosensor containing the defect layer are dependent on the irradiation angle. The maximum values of these parameters occur at irradiation angles of 65 and 47 degrees, with corresponding values of 1056 nm/RIU and 12683, respectively. Therefore, the biosensor with the defect layer is recommended as a suitable candidate for HIV detection.

کلیدواژه‌ها English

Biosensor
Optical sensor
One-dimensional photonic crystals
Human immunodeficiency virus (HIV)
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